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Evil is fissiparous. But itself barren. Melkor could not 'beget', or have any spouse (though he attempted to ravish Arien, this was to destroy and 'distain' her, not to beget fiery offspring). (Morgoth's Ring - Myths Transformed)
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The same holds true for Sauron.
Eomer, to answer your question: Sauron, if he weren't evil, could not have begotten offspring with another Maia, but he could have, presumably, with one of the Eruhini (as Melian did with Thingol). Since he
was 'evil', he could not have reproduced at all in any biological sense.