In that quote from HoME 10, the word "Doom" is not used as negatively as we would see it nowadays - in Tolkien's works, it is often interchangeable with "fate". That would put the intermarriage between Elves and Men on a dramatic, but not quite so tragic level.
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'Mercy!' cried Gandalf. 'If the giving of information is to be the cure of your inquisitiveness, I shall spend all the rest of my days in answering you. What more do you want to know?' 'The whole history of Middle-earth.. .'
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