I believe in "Letters" (although it could be elsewhere)
JRRT says that Queen Beruthiel was finally cast adrift
with her cats. While it's just speculation, one ending
of them could be that they perished at sea (I think I assumed
that was their fate, but there are other possibilities,
such as she sailed the craft) (being a smart- if evil- Numenorean
woman) to south Gondor or Harad and met up with
the Black Numenoreans, and she and/or her
descendants were responsible for attacks on Gondor.
It would seem, for those skilled in such things, a possible
basis for a rpg at least. Any speculations on her fate?